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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A1
All Species:
18.18
Human Site:
S517
Identified Species:
33.33
UniProt:
P19634
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19634
NP_003038.2
815
90763
S517
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Chimpanzee
Pan troglodytes
XP_513239
793
88468
L517
P
F
Q
F
L
D
H
L
L
T
G
I
E
D
I
Rhesus Macaque
Macaca mulatta
XP_001115213
427
46791
F161
P
F
L
Q
S
D
V
F
F
L
F
L
L
P
P
Dog
Lupus familis
XP_535345
816
90951
S518
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
S521
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Rat
Rattus norvegicus
P26431
820
91629
S521
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514675
940
104115
A625
R
S
N
K
K
Q
P
A
V
S
E
E
I
H
C
Chicken
Gallus gallus
Q5ZJ75
574
64115
G308
L
P
Y
G
L
A
E
G
I
S
L
S
G
I
M
Frog
Xenopus laevis
NP_001081553
781
87800
S497
K
K
Q
E
S
K
R
S
I
N
E
E
I
H
S
Zebra Danio
Brachydanio rerio
NP_001106952
653
73606
K387
R
M
V
K
L
S
G
K
D
Q
F
I
V
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
A400
S
Y
G
G
L
R
G
A
I
A
Y
G
L
V
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
F269
L
F
V
L
F
P
Y
F
S
Y
M
L
A
E
G
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
F367
I
Y
L
G
L
E
L
F
T
E
V
E
L
V
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
51.9
95.8
N.A.
92.4
93.2
N.A.
42.5
21.7
73.2
55.4
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
100
86.9
52
97.5
N.A.
95
95.1
N.A.
57.7
39.7
81.8
68.9
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
26.6
6.6
86.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
13.3
20
100
N.A.
100
100
N.A.
66.6
13.3
100
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
16
0
8
0
0
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
16
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
0
0
39
0
8
8
0
0
8
47
54
8
8
0
% E
% Phe:
0
24
0
8
8
0
0
24
8
0
16
0
0
0
0
% F
% Gly:
0
0
8
24
0
0
16
8
0
0
8
8
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
47
0
% H
% Ile:
8
0
0
0
0
0
0
0
54
0
0
16
47
8
8
% I
% Lys:
39
39
0
16
8
39
0
8
0
0
0
0
0
0
0
% K
% Leu:
16
0
16
8
39
0
8
8
8
8
8
16
24
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
39
0
0
0
0
0
% N
% Pro:
16
8
0
0
0
8
8
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
47
8
0
8
0
0
0
8
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
8
39
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
16
8
0
39
8
16
0
8
0
0
8
% S
% Thr:
0
0
0
0
31
0
0
0
8
8
0
0
0
0
31
% T
% Val:
0
0
16
0
0
0
8
0
8
0
8
0
8
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
8
0
0
0
8
0
0
8
8
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _